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The influence of brain death on donor liver and the potential mechanisms of protective intervention

Shui-Jun ZHANG, Tao WANG

Frontiers of Medicine 2011, Volume 5, Issue 1,   Pages 8-14 doi: 10.1007/s11684-011-0109-y

Abstract: The quality of donor organs is closely related to the outcome of the transplantation.conducted in the past 10 years have shown that brain death is associated with effects on the decreased donorHowever, whether the decrease in the viability of donor organs is caused by brain death or by the eventsintroduce the advances and controversies regarding the influence of brain death on the viability of donorlivers and to summarize the mechanisms of the different protective interventions for donor livers.

Keywords： brain death     donor liver    

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Partial liver transplantation

Nianqiao GONG, Xiaoping CHEN

Frontiers of Medicine 2011, Volume 5, Issue 1,   Pages 1-7 doi: 10.1007/s11684-010-0105-7

Abstract: , and living donor liver transplantation, has been developed with several innovative techniques becauseof donor shortage.children and small adult recipients but failing to relieve the overall donor shortage.The first and most important issue involving living donor liver transplantation is donor safety.Before surgery, a series of donor evaluations—including anatomical, liver volume, and liver function

Keywords： partial liver transplantation     reduced-size liver transplantation     split liver transplantation     living donorliver transplantation    

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Machine Perfusion Plus for Extended Criteria Donor Liver Grafts: Making Every Liver Count Review

Zhoucheng Wang, Jack Martin, Jiongjie Yu, Kai Wang, Kourosh Saeb-Parsy, Xiao Xu

Engineering 2024, Volume 32, Issue 1,   Pages 30-41 doi: 10.1016/j.eng.2023.11.003

Abstract:

Transplantation represents the most effective treatment for end-stage liver diseases but is limitedby the shortage of healthy donor organs.Extended criteria donor (ECD) liver grafts are increasingly utilized in clinical practice to mitigate

Keywords： Liver transplantation     Extended criteria donor     Machine perfusion plus     Organ shortage    

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Preliminary experience in adult-to-adult living donor liver transplantation in a single center in China

YAN Lunan, ZENG Yong, WEN Tianfu, ZHAO Jichun, WANG Wentao, YANG Jiayin, XU Mingqing, MA Yukui, CHEN Zheyu, LIU Jiangwen, WU Hong

Frontiers of Medicine 2007, Volume 1, Issue 2,   Pages 136-141 doi: 10.1007/s11684-007-0026-2

Abstract: The aim of this paper is to report the authors experience in performing adult-to-adult living donorliver transplantation (LDLT) by using a modified technique in using grafts of the right lobe of the liverThe graft weight to recipient standard liver volume ratios (GV/SLV) were between 31.86% and 71.68%, among, especially in the reconstruction of the hepatic vein to provide sufficient venous outflow, living donorliver grafts in adults using the right lobe of the liver can become a relatively safe procedure and
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Reducing biliary complications in adult-to-adult living donor liver transplantation using right lobe

YAN Lunan, WEN Tianfu, WANG Wentao, YANG Jiayin, XU Mingqing, CHEN Zheyu, WU Hong

Frontiers of Medicine 2008, Volume 2, Issue 2,   Pages 130-133 doi: 10.1007/s11684-008-0024-z

Abstract: The aim of this paper is to summarize our experience of using right lobe liver grafts to reduce biliarycomplications in adult-to-adult (A-A) living donor liver transplantation (LDLT).From January 2002 to October 2007, 124 adult patients underwent living donor liver transplantation usingBiliary reconstruction for 178 hepatic duct orifices from 124 donor grafts was performed which includedcomplications including six bile leakages (four from the anastomotic site and two from the cut surface of the liver

Keywords： microsurgical     October     improved     success     transplantation    

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Emergency adult living donor right lobe liver transplantation for fulminant hepatic failure

ZHANG Feng, WANG Xuehao, LI Xiangcheng, KONG Lianbao, SUN Beicheng, LI Guoqiang, QIAN Xiaofen, CHEN Feng, WANG Ke, LU Sheng, PU Liyong, LU Ling

Frontiers of Medicine 2007, Volume 1, Issue 3,   Pages 282-286 doi: 10.1007/s11684-007-0054-y

Abstract: Fulminant hepatitis is fatal in most cases and timely liver transplantation is the only effective treatmentThis study evaluates the survival outcomes of patients who underwent living-donor liver transplantation(LDLT) using right lobe liver grafts for fulminant liver failure due to hepatitis B infection.The model for end-stage liver disease (MELD) score of these patients ranged from 16 to 42.Emergency adult living-donor liver transplantation is an effective treatment for fulminant hepatitis

Keywords： alimentary     abnormal     hemorrhage     principal     different    

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Regulation of radicals by hydrogen-donor solvent in direct coal liquefaction

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 12,   Pages 1689-1699 doi: 10.1007/s11705-022-2186-7

Abstract: reaction between the formation and annihilation of coal radical fragments and the effect of hydrogen-donorshowed that the adjustment of the coal radical fragments could be made by the addition of hydrogen-donorThe synergistic mechanism of hydrogen supply and hydrogenolysis of hydrogen-donor solvent was proposed

Keywords： direct coal liquefaction     hydrogen-donor solvent     induced pyrolysis     radical mechanism     density functional    

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γδ T cells in liver diseases

Xuefu Wang, Zhigang Tian

Frontiers of Medicine 2018, Volume 12, Issue 3,   Pages 262-268 doi: 10.1007/s11684-017-0584-x

Abstract: γδ T cells are enriched in the liver and exhibit liver-specific features.fatty liver disease, autoimmune hepatitis, liver fibrosis and cirrhosis, and liver cancer and regenerationWe believe that determining the properties and functions of γδ T cells in liver diseasesenhances our understanding of the pathogenesis of liver diseases and is useful for the design of novelγδ T cell-based therapeutic regimens for liver diseases.

Keywords： γδT cells     liver infection     non-alcoholic fatty liver disease     autoimmune hepatitis     liver fibrosis and cirrhosis     liver cancer     liver regeneration    

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Enhanced photoelectrochemical water splitting with a donor-acceptor polyimide

Frontiers in Energy doi: 10.1007/s11708-023-0910-8

Abstract: owing to its distinct advantages of high visible-light response, facile synthesis, molecularly tunable donor-acceptorsimple spin-coating method was reported, and their PEC properties were investigated using melamine as donor

Keywords： polyimide (PI) film     photoelectrochemistry     band structure engineering     aromatic unit    

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NKT cells in liver diseases

Shasha Zhu, Huimin Zhang, Li Bai

Frontiers of Medicine 2018, Volume 12, Issue 3,   Pages 249-261 doi: 10.1007/s11684-018-0622-3

Abstract: innate-like and tissue-resident lymphocytes, which recognize lipid antigens and are enriched in the livernatural killer T cells and their roles in hepatitis B virus and hepatitis C virus infection, autoimmune liverdiseases, alcoholic liver disease, nonalcoholic fatty liver disease, and hepatocellular carcinoma.and indicate the dynamic alteration in the role of natural killer T cells during the progression of liver

Keywords： natural killer T cells     hepatitis B virus and hepatitis C virus infection     autoimmune liver diseases     alcoholicliver disease     nonalcoholic fatty liver disease     hepatocellular carcinoma    

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Natural killer cells in liver diseases

Meijuan Zheng, Haoyu Sun, Zhigang Tian

Frontiers of Medicine 2018, Volume 12, Issue 3,   Pages 269-279 doi: 10.1007/s11684-018-0621-4

Abstract:

The liver has been characterized as a frontline lymphoid organ with complex immunological featuressuch as liver immunity and liver tolerance.Liver tolerance plays an important role in liver diseases including acute inflammation, chronic infectionThe liver contains a large proportion of natural killer (NK) cells, which exhibit heterogeneity in phenotypicUnder the setting of liver diseases, NK cells are of great importance for stimulating or inhibiting immune

Keywords： natural killer cell     phenotype     immune activation     immune tolerance     liver diseases    

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The “Traditional Chinese medicine regulating liver regeneration” treatment plan for reducing mortalityof patients with hepatitis B-related liver failure based on real-world clinical data

Ling Dai, Xiang Gao, Zhihua Ye, Hanmin Li, Xin Yao, Dingbo Lu, Na Wu

Frontiers of Medicine 2021, Volume 15, Issue 3,   Pages 495-505 doi: 10.1007/s11684-020-0790-9

Abstract: explore the effect and mechanisms of the treatment plan of “traditional Chinese medicine (TCM) regulating liverA total of 457 patients with HBV-related liver failure were retrospectively collected.In addition, there were significant differences in the expression of several cytokines related to liverRLR treatment can decrease jaundice, improve liver function, and significantly reduce the mortality inpatients with HBV-related liver failure.

Keywords： hepatitis B virus-related liver failure     traditional Chinese medicine     liver regeneration     liver regeneration    

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Assessment of liver volume variation to evaluate liver function

Cong Tong, Xinsen Xu, Chang Liu, Tianzheng Zhang, Kai Qu

Frontiers of Medicine 2012, Volume 6, Issue 4,   Pages 421-427 doi: 10.1007/s11684-012-0223-5

Abstract:

In order to assess the value of liver volumetry in cirrhosis and acute liver failure (ALF) patientsto get a regression formula for standard liver volume (SLV) and BSA.It turned out that the mean liver volume of the control group was 1 058±337 cm3.Child A, B level was not reduced, but in Child C level it was significantly reduced with the lowest liverIn conclusion, the CTLV/SLV ratio, which reflects liver volume variations, correlates well with the liver

Keywords： liver volume variation     cirrhosis     acute liver failure (ALF)    

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used as a salvage option for patients with relapsed acute leukemia post-chemotherapy plus modified donor

Frontiers of Medicine 2021, Volume 15, Issue 5,   Pages 728-739 doi: 10.1007/s11684-021-0833-x

Abstract: efficacy of HSCT2 in patients with relapsed/refractory acute leukemia (AL) post-chemotherapy plus modified donor

Keywords： second hematopoietic stem cell transplantation     acute leukemia     relapse     chemotherapy     modified donor    

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Gut microbial balance and liver transplantation: alteration, management, and prediction

Xinyao Tian, Zhe Yang, Fangzhou Luo, Shusen Zheng

Frontiers of Medicine 2018, Volume 12, Issue 2,   Pages 123-129 doi: 10.1007/s11684-017-0563-2

Abstract:

Liver transplantation is a conventional treatment for terminal stage liver diseases.Intestinal barrier destruction is widely observed among patients receiving liver transplant and sufferingThis article reviews the research progress for gut microbial alterations and liver transplantation.microbial alteration and the prediction of possible injuries utilizing microbial alteration during liverand offer a hypothesis on the utilization of microbial alteration in liver transplantation.

Keywords： gut microbial balance     liver transplantation     ischemia–reperfusion     acute rejection    

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Title Author Date Type Operation

The influence of brain death on donor liver and the potential mechanisms of protective intervention

Shui-Jun ZHANG, Tao WANG

Journal Article

Partial liver transplantation

Nianqiao GONG, Xiaoping CHEN

Journal Article

Machine Perfusion Plus for Extended Criteria Donor Liver Grafts: Making Every Liver Count

Zhoucheng Wang, Jack Martin, Jiongjie Yu, Kai Wang, Kourosh Saeb-Parsy, Xiao Xu

Journal Article

Preliminary experience in adult-to-adult living donor liver transplantation in a single center in China

YAN Lunan, ZENG Yong, WEN Tianfu, ZHAO Jichun, WANG Wentao, YANG Jiayin, XU Mingqing, MA Yukui, CHEN Zheyu, LIU Jiangwen, WU Hong

Journal Article

Reducing biliary complications in adult-to-adult living donor liver transplantation using right lobe

YAN Lunan, WEN Tianfu, WANG Wentao, YANG Jiayin, XU Mingqing, CHEN Zheyu, WU Hong

Journal Article

Emergency adult living donor right lobe liver transplantation for fulminant hepatic failure

ZHANG Feng, WANG Xuehao, LI Xiangcheng, KONG Lianbao, SUN Beicheng, LI Guoqiang, QIAN Xiaofen, CHEN Feng, WANG Ke, LU Sheng, PU Liyong, LU Ling

Journal Article

Regulation of radicals by hydrogen-donor solvent in direct coal liquefaction

Journal Article

γδ T cells in liver diseases

Xuefu Wang, Zhigang Tian

Journal Article

Enhanced photoelectrochemical water splitting with a donor-acceptor polyimide

Journal Article

NKT cells in liver diseases

Shasha Zhu, Huimin Zhang, Li Bai

Journal Article

Natural killer cells in liver diseases

Meijuan Zheng, Haoyu Sun, Zhigang Tian

Journal Article

The “Traditional Chinese medicine regulating liver regeneration” treatment plan for reducing mortalityof patients with hepatitis B-related liver failure based on real-world clinical data

Ling Dai, Xiang Gao, Zhihua Ye, Hanmin Li, Xin Yao, Dingbo Lu, Na Wu

Journal Article

Assessment of liver volume variation to evaluate liver function

Cong Tong, Xinsen Xu, Chang Liu, Tianzheng Zhang, Kai Qu

Journal Article

used as a salvage option for patients with relapsed acute leukemia post-chemotherapy plus modified donor

Journal Article

Gut microbial balance and liver transplantation: alteration, management, and prediction

Xinyao Tian, Zhe Yang, Fangzhou Luo, Shusen Zheng

Journal Article